16: Elevated Intraocular Pressure is a Common Complication during Active Microbial Keratitis

HalilAtes 27. Haziran 2011 09:25

Mikrobial keratit vakalarında daha dikkatli izlem yapmamız gerekliliğini vurgulayan yeni bir çalışmayı bilgilerinize sunuyorum

Purpose

To determine the incidence, risk factor, and outcomes of elevated intraocular pressure (IOP) during active microbial keratitis.

Design

Retrospective cohort study.

Methods

One hundred eighty-four patients with culture-proven microbial keratitis examined from January 2003 through December 2007 were included. High IOP was defined as IOP of 22 mm Hg or higher measured during the episode of active keratitis. The control group consisted of eyes with microbial keratitis whose IOP remained less than 22 mm Hg. Twelve factors were evaluated by univariate and multivariate analyses to determine whether any were associated with increased IOP. The incidence, risk factors, microbial profile, the necessity of therapeutic surgery, time to resolution, and final visual acuity were compared between the high IOP group and the control group.

Results

High IOP (mean, 29.1 mm Hg; range, 22 to 51 mm Hg) occurred in 52 (28%) of 184 patients with active corneal infection. Prior ocular surgery, diabetes mellitus, and ulcer size of 4.0 mm or larger were associated with IOP elevation (P ≤ .013). Surgical interventions were necessary in 19 (39%) of 49 patients in the high IOP group and in 14 (11%) of 129 patients in the control group (P < .0001). Time to ulcer resolution was longer in the high IOP group (mean, 50.1 ± 53.2 days) than in the control (mean, 31.6 ± 42.0 days; P = .005). Final visual acuity of 20/40 or better was achieved by more patients in the control group (47%) than in the high IOP group (20%; P < .001).

Conclusions

Elevated IOP was detected in a significant proportion of patients with active microbial keratitis and was associated with poorer outcomes. Routine IOP check should be performed to avoid possible optic nerve damage.

 

AJO: Siamak Zarei-Ghanavati, Elmira Baghdasaryan, Arturo Ramirez-Miranda

Etiketler: ,

glokomda kornea | yayın

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Prof. Dr. Halil Ateş

 

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